Special populations

Description: 
This Medication Guide provides basic information about Butrans, the prescription medicine used for the management of moderate to severe chronic pain in patients requiring an around-the-clock opioid analgesic for a long period of time.
Source: 
Food and Drug Administration (FDA)
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This web page provides brief recommendations for monitoring patients undergoing buprenorphine treatment using liver function tests, and the proper actions to take if a patient develops hepatitis.
Source: 
PCSS Guidance
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Description: 
This consent form -- reproduced with permission from the Boston Medical Center -- can be used with your pregnant patients who want to continue taking buprenorphine during pregnancy.
Source: 
Boston Medical Center
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Description: 
This clinical guidance from the PCSS provides facts and tips about treating adolescent patients with buprenorphine.
Source: 
PCSS-Buprenorphine
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Presently, methadone is the recommended treatment for opioid-dependent pregnant women, but is associated with neonatal abstinence syndrome (NAS). NAS is characterized by opioid withdrawal symptoms in the newborn, which often requires longer hospitalization and treatment. Buprenorphine, FDA-approved in 2002 for the treatment of opioid dependence in non-pregnant individuals, hasn't been extensively studied during pregnancy. Yet, a new study in the New England Journal of Medicine (NEJM) found that buprenorphine offers an alternative to methadone in the treatment of opioid-dependent pregnant women. The study compared buprenorphine to methadone in 131 mothers and their newborns at eight international sites.
Source: 
New England Journal of Medicine
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Description: 
This document discusses the evidence for buprenorphine treatment of opioid dependent adolescents and young adults. It provides treatment recommendations, and highlights special issues that should be considered when treating this special population.
Source: 
Physician Clinical Support System (PCSS)
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Description: 
This information brief discusses the abuse of prescription drugs by young people, commonly abused prescription drugs, and diversion of said drugs.
Source: 
National Drug Intelligence Center
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Description: 
This guideline offers guidelines on treating pregnant, substance-using women, with sections on Alcohol and Other Drug Treatment Guidelines for Pregnant, Substance-Using Women, Medical Guidelines for Pregnant, Substance-Using Women, and Legal and Ethical Guidelines for the Care of Pregnant, Substance-Using Women.
Source: 
U.S Department of Health and Human Services
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