Resource Center: Induction and dosing

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Signs and Symptoms of Opioid Intoxication and Withdrawal
Description: 
A description of the signs of opiate withdrawal useful for physicians in determining withdrawal during medically supervised detoxification.
Source: 
National Center for Biotechnology Information
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TIP 40 Chapter 4: Treatment Protocols
Description: 
Discusses protocols for office-based buprenorphine treatment, including the administering of the drug itself, devising a treatment plan, and choosing an appropriate frequency for visits.
Source: 
Substance Abuse and Mental Health Services Administration (SAMHSA)
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Opioid Withdrawal Syndrome With Buprenorphine Induction
Description: 
Information on why your patient should be in withdrawal before beginning buprenorphine induction.
Source: 
Substance Abuse and Mental Health Services Administration (SAMHSA)
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Substance Abuse & Mental Health Services Administration
Description: 
The Substance Abuse and Mental Health Services Administration (SAMHSA) provides this website so that physicians can improve the deliver and financing of prevention, treatment and recovery support services to patients.
Source: 
Substance Abuse and Mental Health Services Administration (SAMHSA)
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Drug Safety Information for Providers and Patients: Buprenorphine tablets
Description: 
Buprenorphine tablets are approved for the treatment of opiate dependence. Buprenorphine treats opiate addiction by preventing symptoms of withdrawal from heroin and other opiates.
Source: 
Food and Drug Administration (FDA)
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PCSS-B Guidance: Treatment of Acute Pain in Patients Receiving Buprenorphine/Naloxone
Description: 
This article provides guidance on the management and treatment of acute pain in patients receiving buprenorphine/naloxone.
Source: 
Physician Clinical Support System (PCSS)
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Buprenorphine Dosing Algorithms

Description: 
A series of flow charts displaying the steps that should be followed when inducting a new patient into buprenorphine treatment.

Flow charts are included for patients addicted to short- and long-acting opioids, for non-physically dependent patients, and for patients switching from buprenorphine to buprenorphine/naloxone.

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PCSS-B Guidance: Buprenorphine Induction
Description: 
This document discusses the logistics of successful buprenorphine induction, offering insight into clinical questions that should be addressed, the goal of induction, general principles, and recommendations based on low and high levels of evidence. Recommendations are included for both in-office and at-home inductions.
Source: 
Physician Clinical Support System (PCSS)
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DSM IV Criteria for Opioid Withdrawal

Description: 
Lists DSM-IV Criteria for Opioid Withdrawal

A. Either of the following:

  1. cessation of (or reduction in) opioid use that has been heavy and prolonged (several weeks or longer)

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DSM-IV Criteria for Opioid Withdrawal

Description: 
Lists the clinical criteria for opioid withdrawal.

DSM-IV Criteria for Opioid Withdrawal

A. Either of the following:

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