Resource Center: General information - buprenorphine

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How Opioids and Buprenorphine Work

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How opioids and buprenorphine affect the brain.

This illustrated patient handout outlines how opioids and buprenorphine affect the brain.

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Starting Suboxone®: A Patient's Guide

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This patient handout explains what each patient should do before, during, and after induction with Suboxone®.

Starting Suboxone: A Patient's Guide

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ASAM Patient Placement Criteria

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The ASAM Patient Placement Criteria for the Treatment of Substance-Related Disorders, Second Edition-Revised (Mee-Lee et al., 2001) lists the 5 basic levels of care available for adult substance users. These levels of care range from Early Intervention (for at-risk individuals) to Medically Managed Intensive Inpatient Treatment (for patients with severe disorders who require around-the-clock care). The Patient Placement Criteria classifies opioid maintenance therapy as a Level I treatment since it is most often conducted in outpatient settings.

According to the Patient Placement Criteria, the following 6 patient dimensions should be considered when formulating a treatment plan (Mee-Lee et al., 2001):

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Generation Rx: Fighting Addiction with a Pill
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This 2007 video segment from CBS News discusses the widespread problem of prescription drug dependence and how buprenorphine can help.
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CBS News
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The cost-effectiveness of buprenorphine maintenance therapy for opiate addiction in the United States
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This study examines the cost-effectiveness of buprenorphine maintenance therapy for treating opioid addiction.
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Addiction
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PCSS Clinical Guidances: An Educational Resource for Those Treating Patients with Opioid Dependence
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This website, funded by SAMHSA, is designed to help physicians to implement office-based buprenorphine treatment using a national network of trained physician mentors.
Source: 
Physician Clinical Support System (PCSS)
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PCSS-B Guidance: Treatment of Acute Pain in Patients Receiving Buprenorphine/Naloxone
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This article provides guidance on the management and treatment of acute pain in patients receiving buprenorphine/naloxone.
Source: 
Physician Clinical Support System (PCSS)
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DSM-IV Criteria for Opioid Withdrawal

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DSM-IV Criteria for Opioid Withdrawal.

Opioid withdrawal occurs in opioid-dependent individuals who reduce or stop their opioid use or who take an opioid antagonist (precipitated withdrawal).

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Pharmacology of the Buprenorphine/Naloxone Combination

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Buprenorphine/naloxone combination tablets are designed to minimize the potential for abuse of buprenorphine. When taken as indicated (sublingually), the naloxone component has virtually no effect on the patient; however, when injected, the naloxone component attenuates buprenorphine's reinforcing effects and possibly will induce withdrawal (Johnson et al., 2003).

In addition to buprenorphine monotherapy tablets, tablets combining 4 parts buprenorphine and 1 part naloxone (a mu opioid antagonist) are also being used in maintenance treatment for opioid depen

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Therapy Progress Report
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This worksheet checks the progress of a patient's suboxone therapy. It has two main sections: one filled out by the patient, and the other by a physician or other medical professional.
Source: 
Reckitt Benckiser
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