Basic Induction and Dosing Guidelines

Standardized dosing protocols are available, but induction should be conducted through careful observation and the dosing should be adjusted accordingly

Buprenorphine induction and maintenance doses may differ for each patient. When planning induction, first consider whether a patient is dependent upon short-acting opioids (e.g. heroin, most prescription narcotics) versus long-acting opioids (e.g. methadone). It will take longer for patients who are dependent on long-acting opioids to prepare for induction (longer abstinence period in the days prior to induction).

Most patients can be started and maintained on the buprenorphine/naloxone combination tablet or filmstrip (brand name: Suboxone®). The combination formulation contains a 4:1 ratio of buprenorphine and naloxone. The monotherapy tablet should only be used in those who are pregnant or have a naloxone allergy.